Eosinophilic pneumonia adult cause

Eosinophilic esophagitis is an inflammation swelling of the esophagus the tube connecting the mouth to the stomach , caused by a specific white blood cell the eosinophil. The number of people affected is about 1 in 10, though health officials think this number is underreported. Nearly three-quarters of cases occur in white males. This is a relatively newly recognized disease that has been increasingly diagnosed in adults and children over the past decade. Patients with eosinophilic esophagitis may have symptoms such as heartburn , regurgitation, chest pain, and trouble swallowing.

Acute eosinophilic pneumonia AEP is an uncommon acute respiratory illness of varying severity that includes presentation as acute respiratory distress syndrome with fatal outcome. AEP may be idiopathic, but identifiable causes include smoking and other inhalational exposures, medications, and infections. The pathogenesis of AEP is poorly understood but likely varies depending on the underlying cause. Airway epithelial injury, endothelial injury, and release of IL are early events that subsequently promote eosinophil recruitment to the lung; eosinophilic infiltration and degranulation appear to mediate subsequent lung inflammation and associated clinical manifestations.

Eosinophilic pneumonia is a disease in which an eosinophil , a type of white blood cell , accumulates in the lungs. These cells cause disruption of the normal air spaces alveoli where oxygen is extracted from the atmosphere. Several different kinds of eosinophilic pneumonia exist and can occur in any age group. The most common symptoms include cough , fever , difficulty breathing , and sweating at night. Eosinophilic pneumonia is diagnosed by a combination of characteristic symptoms, findings on a physical examination by a health provider, and the results of blood tests and X-rays.

Chronic eosinophilic pneumonia CEP is an idiopathic condition characterized by the alveoli filling with an inflammatory, eosinophil -rich infiltrate. Classically on imaging, it appears as chronic consolidation with upper zone and peripheral predominance. There is a greater female predilection 1. Histology typically shows accumulation of eosinophils and lymphocytes in the alveoli and interstitium, with interstitial fibrosis. An organizing pneumonia pattern or an eosinophilic abscess may also be seen.